Maximum Value Attribute-Based Extra Trees, XGBoost, and LightGBM for Early Disease Prediction
Keywords:
Disease Prediction, Machine Learning, Rough Set Theory, Maximum Value Attribute, Extra Trees, XGBoost, LightGBM, Feature Selection, Hybrid MVA, Clinical SymptomsAbstract
The evolution of intelligent healthcare systems has increased the importance of machine learning techniques in timely prediction of heart disease by using clinical and medical data. In recent years machine Learning techniques have been used widely in disease prediction systems due to their ability to examine complex medical patterns and also for better diagnostic accuracy. Many machine learning classifiers achieve strong predictive performance but still acquire high computational power and longer execution time during their training and testing phases. The ensemble learning algorithms such as Extra Trees, Extreme Gradient boosting and LightGBM have excellent performance in prediction of data due to their high classification accuracy and robustness. The main problem is that these models often suffer from high iteration counts, longer execution time and the inclusion of irrelevant or redundant features which may affect prediction efficiency and the overall performance of a model. To address these limitations, this research paper introduces a Rough Set Theory which is totally based on hybrid maximum value attribute (MVA). Hybrid MVA is a feature selection method that combines cardinality based ranking for categorical attributes and variance based ranking for continuous attributes in order to choose the most relevant features before training the models and predict heart disease in an efficient manner.The proposed models evaluate three techniques that are hybrid maximum value attribute Extra trees (MVA ET), hybrid maximum value Attribute XGBoost (MVA XGBoost) and hybrid maximum value attribute LightGBM (MVA LightGBM). This hybrid MVA method improves the performance of the model and improves computational efficiency by selecting the most relevant categorical and continuous features and removes irrelevant ones. The models are implemented using Python in Jupyter Notebook. The dataset is obtained from Kaggle platform which is titled as “Synthetic Heart Disease Prediction Dataset” that contains 50000 records and 20 features. The standard performance evaluation metrics including accuracy, precision, recall, F1 score and execution time are used to measure the success of the proposed approach. This report compares standard models against hybrid MVA across various train and test data distributions. The experimental evaluation is performed using accuracy, precision, recall, F1-score, execution time and iteration analysis to measure model effectiveness comprehensively and Experimental results show that the hybrid MVA based models outperforms the traditional classifiers in terms of prediction accuracy, computational efficiency and feature optimization. It reduces the feature dimensionality from 20 to 13 features, i.e., a 35% reduction in the input feature space before model training. For the Extra Trees classifier, the average iteration steps decreased from 46,787 to 31,040, corresponding to a 33.7% reduction in computational complexity. Similarly, training and execution time were also reduced in Hybrid MVA Extra Trees. The Hybrid MVA XGBoost model and Hybrid MVA LightGBM reduced the average iteration steps from 4,560 to 2,964, corresponding to a 35% reduction, while also reducing training and execution times. The Hybrid MVA Extra Trees model achieved an average accuracy of 99.07%, while Hybrid MVA XGBoost and Hybrid MVA LightGBM maintained average accuracies of 99.73% and 99.57%, respectively. Among the proposed approaches, Hybrid MVA XGBoost provided the best balance between predictive performance and computational efficiency.
References
K. Gulzar, B. A. Hassan, M. Abbas, Z. Ahmad, and M. A. and H. Ullah, “Maximum Value Attribute based Decision Tree and Random Forest for COVID-19 Prediction,” Int. J. Innov. Sci. Technol., vol. 7, no. 4, pp. 2940–2954, 2025, Accessed: Aug. 17, 2026. [Online]. Available: https://ideas.repec.org/a/abq/ijist1/v7y2025i4p2940-2954.html
Das, P.; Sarker, P.; Tiang, J.-J.; Nahid, A.-A., “Dengue Fever Classification Integrating Bird Swarm Algorithm with Gradient Boosting Classifier Along with Feature Selection and SHAP–DiCE Based Interpretability.,” Appl. Sci, vol. 15, no. 11413, 2025, doi: https://doi.org/10.3390/app152111413.
I. Izaz Ahmmed Tuhin, A.K.M.Fazlul Kobir Siam, Md Mahfuzur Rahman Shanto, Md Rajib Mia, “‘An interpretable machine learning model for dengue detection with clinical hematological data,’” Healthc. Anal., vol. 8, 2025, doi: https://doi.org/10.1016/j.health.
T. Ashika and G. H. Grace, “Enhancing Classification Performance through Rough Set Theory Feature Selection: A Comparative Study across Multiple Datasets,” Eur. J. Pure Appl. Math., vol. 18, no. 2, Apr. 2025, doi: 10.29020/NYBG.EJPAM.V18I2.5934.
T. Ashika and G. Hannah Grace, “Enhancing heart disease prediction with stacked ensemble and MCDM-based ranking: an optimized RST-ML approach,” Front. Digit. Heal., vol. 7, p. 1609308, Jun. 2025, doi: 10.3389/FDGTH.2025.1609308/TEXT.
D. Dewi, B.E.; Kartika, A.A.A.; Faridah, A.T.; Ewaldo, M.F.; Hafizh, A.M.; Chrysilla, V.; Frederich, J.; Surya, A.; Aryani, “Development of a Machine Learning Model for Predicting Dengue Cases and Severity in Indonesia,”,” Appl. Sci, vol. 16, no. 1436, 2026, doi: https://doi.org/10.3390/app16031436.
A. M. Khan S, Ullah R, Khan A, Wahab N, Bilal M, ““Analysis of dengue infection based on Raman spectroscopy and support vector machine (SVM),” Biomed Opt Express, vol. 7, p. 2249, 2016, doi: doi: 10.1364/BOE.7.002249.
O. E. Kumar Y, Liang C, Bo Z, Rajapakse JC, ““Serum Proteome and Cytokine Analysis in a Longitudinal Cohort of Adults with Primary Dengue Infection Reveals Predictive Markers of DHF,” PLoSNegl Trop Dis, vol. 6, 2021, doi: doi: 10.1371/journal.pntd.0001887.
N. Zhao et al., “‘Machine learning and dengue forecasting: Comparing random forests and artificial neural networks for predicting dengue burden at national and sub-national scales in Colombia,’” ,” PLoSNegl Trop Dis, vol. 14, pp. 1–16, 2020, doi: , doi: 10.1371/journal.pntd.0008056.
S. Subudhi et al., “Comparing machine learning algorithms for predicting ICU admission and mortality in COVID-19,” npj Digit. Med. 2021 41, vol. 4, no. 1, pp. 87-, May 2021, doi: 10.1038/s41746-021-00456-x.
D. O. Uchenna J. Nzenwata1* , Emokiniovo Edwin1, Emmanuel A. Chukwu2 and C. E. Johnson O. Hinmikaiye1, “Extra Trees Model for Heart Disease Prediction,” J. Data Anal. Inf. Process., vol. 13, p. . 125–139, 2025, doi: https://doi.org/10.4236/jdaip.2025.132008.
B. Liu, M. F. Hossain, and S. Hossain, “A comparative evaluation of multiple machine learning approaches for forecasting dengue outbreaks in Bangladesh,” Sci. Reports 2025 151, vol. 15, no. 1, pp. 35931-, Oct. 2025, doi: 10.1038/s41598-025-19752-7.
M. A. & R. D. . Bam Bahadur Sinha, “LightGBM empowered by whale optimization for thyroid disease detection,”,” Int. J. Inf. Technol. (Singapore), vol. 15, pp. 2053–2062, 2023, doi: doi.org/10.1007/s41870-023-01261-3.
J. Uddin, R. Ghazali, M. M. Deris, U. Iqbal, and I. A. Shoukat, “A novel rough value set categorical clustering technique for supplier base management,” Comput. 2021 1039, vol. 103, no. 9, pp. 2061–2091, Apr. 2021, doi: 10.1007/S00607-021-00950-W.
A. Khakharia et al., “Outbreak Prediction of COVID-19 for Dense and Populated Countries Using Machine Learning,” Ann. Data Sci. 2020 81, vol. 8, no. 1, pp. 1–19, Oct. 2020, doi: 10.1007/S40745-020-00314-9.
W. M. Alhadi Bustamam 1,*, Hengki Muradi 2, W. Mangunwardoyo, S. orgGoogle. Scholar, and 3 andBeti E. Dewi 4, “Comparison of dengue predictive models developed using artificial neural network and discriminant analysis with small dataset,” Appl. Sci., vol. 11, no. 3, 2021, doi: https://doi.org/10.3390/app11030943.
H. Fayyoumi, E., Idwan, S., & AboShindi, “Machine Learning and Statistical Modelling for Prediction of Novel COVID-19 Patients Case Study: Jordan,”,” Jordan, vol. 11, no. 5, 2020, doi: DOI: https://doi.org/10.14569/IJACSA.2020.0110518.
M. C. Y. H. K. H. L. W. L. W. Wang, “Disease Prediction by Machine Learning over Big Data from Healthcare Communities,”,” IEEE Access, vol. 5, p. . 8869-8879, 2017, doi: doi: 10.1109/ACCESS.2017.2694446.
E. Arianyan, N. Gholipour, D. Maleki, N. Ghorbani, A. Sepahvand, and P. Goudarzi, “A Systematic Review and Classification of HPC-Related Emerging Computing Technologies,” Electron. 2025, Vol. 14, Page 2476, vol. 14, no. 12, p. 2476, Jun. 2025, doi: 10.3390/ELECTRONICS14122476.
A. A. Alrajhi et al., “Data-Driven Prediction for COVID-19 Severity in Hospitalized Patients,” Int. J. Environ. Res. Public Health, vol. 19, no. 5, Mar. 2022, doi: 10.3390/IJERPH19052958.
L. J. Muhammad, E. A. Algehyne, S. S. Usman, A. Ahmad, C. Chakraborty, and I. A. Mohammed, “Supervised Machine Learning Models for Prediction of COVID-19 Infection using Epidemiology Dataset,” SN Comput. Sci. 2020 21, vol. 2, no. 1, pp. 11-, Nov. 2020, doi: 10.1007/S42979-020-00394-7.
Y. Zoabi and N. Shomron, “COVID-19 diagnosis prediction by symptoms of tested individuals: a machine learning approach,” medRxiv, p. 2020.05.07.20093948, May 2020, doi: 10.1101/2020.05.07.20093948.
D. Arumuganainar, “Extra Tree Classifier Predicts an Interactome Hub Gene as HSPB1 in Oral Cancer: A Bioinformatics Analysis,” Cureus, May 2024, doi: 10.7759/CUREUS.59863.
Y. Gao et al., “Machine learning based early warning system enables accurate mortality risk prediction for COVID-19,” Nat. Commun. 2020 111, vol. 11, no. 1, pp. 5033-, Oct. 2020, doi: 10.1038/s41467-020-18684-2.
D. K. Sharma, M. Subramanian, P. Malyadri, B. S. Reddy, M. Sharma, and M. Tahreem, “Classification of COVID-19 by using supervised optimized machine learning technique,” Mater. Today Proc., vol. 56, pp. 2058–2062, Jan. 2022, doi: 10.1016/J.MATPR.2021.11.388.
M. E. Haque, S. M. Jahidul Islam, J. Maliha, M. S. Hossan Sumon, R. Sharmin, and S. Rokoni, “Improving Chronic Kidney Disease Detection Efficiency: Fine Tuned CatBoost and Nature-Inspired Algorithms with Explainable AI,” 2025 IEEE 14th Int. Conf. Commun. Syst. Netw. Technol. CSNT 2025, pp. 811–818, Apr. 2025, doi: 10.1109/CSNT64827.2025.10968421.
M. N. Islam, M. M. H. Rimon, S. S.-E.-A. Shamim, Z. M. Fahad, M. J. I. Mony, and M. J. U. Chowdhury, “An Improved Ensemble-Based Machine Learning Model with Feature Optimization for Early Diabetes Prediction,” Nov. 2025, Accessed: Aug. 18, 2026. [Online]. Available: https://arxiv.org/pdf/2512.02023
Ahmet ÇELİK, “Predicting Diagnosis Of Covid-19 Disease With Adaboost And Naive Bayes Machine Learning Algorithms,” J. Eng. Sci. Des., vol. 10, no. 4, 2022, [Online]. Available: https://dergipark.org.tr/en/download/article-file/1901380
“Appositeness of Hoeffding tree models for breast cancer classification | Journal of Current Science and Technology.” Accessed: Aug. 18, 2026. [Online]. Available: https://ph04.tci-thaijo.org/index.php/JCST/article/view/253
M. S. Satu et al., “Short-Term Prediction of COVID-19 Cases Using Machine Learning Models,” Appl. Sci. 2021, Vol. 11, Page 4266, vol. 11, no. 9, p. 4266, May 2021, doi: 10.3390/APP11094266.
A. Z. Baratpur, H. Vahdat-Nejad, E. Arslan, J. Hassannataj Joloudari, and S. Gaftandzhieva, “Coronary artery disease prediction using Bayesian-optimized support vector machine with feature selection,” Front. Netw. Physiol., vol. 5, p. 1658470, Dec. 2025, doi: 10.3389/FNETP.2025.1658470/TEXT.
D. N. M. S. R. S. K.Tharageswari, “A Robust Disease Prediction System Using Hybrid Deep Neural Networks,” Libr. Prog. Int., vol. 44, no. 3, pp. 28383–28398, Nov. 2024, doi: 10.48165/BAPAS.2024.44.2.1.
K. Alsharabi, Y. Bin Salamah, A. M. Abdurraqeeb, M. Aljalal, and F. A. Alturki, “EEG Signal Processing for Alzheimer’s Disorders Using Discrete Wavelet Transform and Machine Learning Approaches,” IEEE Access, vol. 10, pp. 89781–89797, 2022, doi: 10.1109/ACCESS.2022.3198988.
A. Alariyibi, M. El-Jarai, and A. Maatuk, “Evaluating The Accuracy of Classification Algorithms for Detecting Heart Disease Risk,” Mach. Learn. Appl. An Int. J., vol. 10, no. 4, pp. 01–12, Dec. 2023, doi: 10.5121/mlaij.2023.10401.
M. S. Alkhasawneh, “Hybrid Cascade Forward Neural Network with Elman Neural Network for Disease Prediction,” Arab. J. Sci. Eng. 2019 4411, vol. 44, no. 11, pp. 9209–9220, Apr. 2019, doi: 10.1007/S13369-019-03829-3.
A. Y. Yıldız and A. Kalayci, “Gradient Boosting Decision Trees on Medical Diagnosis over Tabular Data,” 2025 IEEE Conf. AI Data Anal. ICAD 2025, Aug. 2025, doi: 10.1109/ICAD65464.2025.11114069.
Y. On et al., “Classification of Mitral Regurgitation from Cardiac Cine MRI Using Clinically-Interpretable Morphological Features,” Lect. Notes Comput. Sci., vol. 15448 LNCS, pp. 245–256, 2025, doi: 10.1007/978-3-031-87756-8_25/SAVE-RESEARCH.
S. Noor, S. A. AlQahtani, S. Khan, S. Noor, S. A. AlQahtani, and S. Khan, “Chronic liver disease detection using ranking and projection-based feature optimization with deep learning,” AIMS Bioeng. 2025 150, vol. 12, no. 1, pp. 50–68, 2025, doi: 10.3934/BIOENG.2025003.
Y. Hu and A. Chaddad, “SHAP-Integrated Convolutional Diagnostic Networks for Feature-Selective Medical Analysis,” Mar. 2025, Accessed: Aug. 17, 2026. [Online]. Available: https://arxiv.org/pdf/2503.08712
B.-C. Phan, T. Ma, H.-H. Nguyen, and T.-N. Do, “BoMGene: Integrating Boruta-mRMR feature selection for enhanced Gene expression classification,” Oct. 2025, Accessed: Aug. 17, 2026. [Online]. Available: https://arxiv.org/pdf/2510.00907
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